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isotopic perturbation, method of definition

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NMR shift difference measurement of the isotope effect on a fast (degenerate) equilibrium between two, except for isotopic substitution, species which are equivalent. This can be used to distinguish a rapidly equilibrating mixture with time-averaged symmetry from a single structure with higher symmetry. SIEHL (1987).


See also:

isovalent hyperconjugation definition
Isometric, Anisometric definition
item header definition
isotope effect, primary definition
isonitroso compounds definition