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Cooperativity definition
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Cooperativity is the interaction process by which binding of a ligand to one site on a macromolecule (enzyme, receptor, etc.) influences binding at a second site, e.g. between the substrate binding sites of an allosteric enzyme. Cooperative enzymes typically display a sigmoid (S-shaped) plot of the reaction rate against substrate concentration. (See also Allosteric binding sites).

See also:
critical area definition
Cooperativity definition
coumarins definition
coulombic attraction definition
Coordination Isomers definition
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